San Francisco Giants second baseman Thairo Estrada (hamstring) is not in the Giants' lineup for their Friday night tilt against the Pittsburgh Pirates. Estrada was removed from Wednesday's game against the Mets after dealing with hamstring tightness. As of now, Estrada is considered day-to-day. The 28-year-old is slashing .232/.253/.400 on the year so his impact to the Giants and fantasy managers' lineups may be fairly negligible. Tyler Fitzgerald is getting the start in his place and will bat eighth. Should Estrada return this weekend he would see Martin Perez on Saturday and Pirates rookie Jared Jones on Sunday.

Kansas City Royals shortstop Bobby Witt Jr. notched three RBI in the Royals 8-0 win over the Detroit Tigers on Friday afternoon. Witt Jr. went 1-4 with a two RBI triple and an RBI sacrifice fly. He also scored a run in the Royals' seven-run ninth. The 23-year-old now has 14 RBI on the season with a .915 OPS and leads the league in triples with four. As a top option in fantasy baseball, Witt Jr. is delivering for fantasy managers who took him in the first round. Witt Jr. faces Casey Mize on Saturday and will have a tough matchup against Tigers ace Tarik Skubal on Sunday.

Toronto Blue Jays right-hander Alek Manoah (shoulder) will make another minor-league rehab start for Triple-A Buffalo next Tuesday. Not only is Manoah rehabbing from a right-shoulder injury, but he hasn't been good in three of his four rehab starts to this point. In his last outing with Buffalo on Wednesday, the 26-year-old allowed six runs on seven hits while walking four in just three innings of work. Even if Manoah is getting healthier, his performances don't exactly endorse him for a big-league call-up to enter Toronto's starting rotation. Hi rehab assignment will be up on May 6, but it wouldn't be a surprise to see him activated from the injured list and optioned back to Buffalo. Manoah's 2023 nightmare season has so far carried over to 2024.

Tampa Bay Rays outfielder Josh Lowe (oblique) reportedly is feeling great during his minor-league rehab assignment. The 26-year-old says he's ready to return whenever the teams feels like bringing him back. In six games, Lowe is slashing .227/.346/.364 with a homer, and five RBI during his rehab stint. It sounds like Lowe is ready to return and could be activated off the injured list any day now.

Tampa Bay Rays relief pitcher Colin Poche (back) has been placed on the 15-day injured list on Friday. The move is retroactive to April 24th with Poche dealing with back tightness. The organization has not given a timetable for how long Poche will be sidelined. This is a hit to the Rays bullpen with Pete Fairbanks already sidelined as well. The loss of these two pitchers should mean increased save chances for Jason Adam and Garrett Cleavinger.

Los Angeles Angels infielder Brandon Drury (knee) is back in the starting lineup on Friday against the visiting Minnesota Twins and right-hander Bailey Ober, serving as the designated hitter and batting fifth. Miguel Sano is at third base for the Halos and is hitting cleanup. Drury didn't start at all during the recent three-game series against the Baltimore Orioles due to a knee injury but appeared on Wednesday late in the game and struck out in his only plate appearance. Fantasy managers in deeper leagues will be hoping that Drury can show some signs of life at the plate this weekend, as he's started the 2024 season with a weak .194/.270/.269 slash line with a home run and four RBI in 74 plate appearances. He's never faced Ober in his career.

Atlanta Braves outfielder Jarred Kelenic is out of the starting lineup on Friday with the team facing a left-handed pitcher. Veteran Adam Duvall will instead get the start in left field and will bat ninth against the visiting Cleveland Guardians and left-hander Logan Allen. Kelenic is hitting a strong .314 (16-for-51), although he has yet to clear the fences and has driven in only three runs in his first year in Atlanta. He's also only had one plate appearance against a southpaw this year, so fantasy managers should continue to expect him to sit regularly when Atlanta opposes a lefty. Duvall is a career .233 hitters against lefties in 921 plate appearances with 47 homers and 132 RBI. He has two home runs on the season but is a low-upside DFS play in the nine-hole against a pitcher he's never faced in his career.

Washington Nationals manager Dave Martinez wants to ease catcher Keibert Ruiz in now that he's returned from a bad case of influenza that caused him to lose 18-20 pounds. It will also give the skipper the opportunity to keep catcher Riley Adams' bat in the lineup on a regular basis after he posted a .793 OPS when he caught 11 of the last 13 games with Ruiz out. "We're definitely going to use him," Martinez said. "One, let him catch. And two, we can also DH Keibert like we've done in the past and let him continue to catch. He's done a great job. He's learned a lot over the years. He's really coming into his own. It's good to have him, to watch him play and to watch him get better every day he's out there." As long as the 27-year-old continues to play several times a week, he'll be valuable in two-catcher fantasy leagues.

Boston Red Sox first baseman Triston Casas (rib) said he avoided a fracture in his left rib cage but instead suffered torn cartilage, which is an unusual injury without contact. Casas was told by a doctor that he "created my own car crash." He has a wide timetable for a return between three and nine weeks to start cardio activity/strengthening. Casas said he's very optimistic that he'll return this year, but fantasy managers could be waiting for a while to get the 24-year-old left-handed slugger back. The former 26th overall pick in 2018 is worth stashing in all fantasy formats, though, as he was already up to six home runs in his first 78 at-bats of 2024. For the foreseeable future, Bobby Dalbec should continue to see most of the playing time at first base in Boston, with Rob Refsnyder also potentially filling in.

Minnesota Twins right-hander Bailey Ober will look to keep rolling on Friday when he hits the road for a matchup with the Los Angeles Angels. The towering 6-foor-9 righty was lit up for eight earned runs in just 1 1/3 innings in his season debut on March 31 but has since allowed all of two earned runs over his last three starts spanning 17 innings of work. He dominated the Tigers over his last two starts, tossing 12 innings of one-run ball by allowing just five hits and one walk against nine punchouts. He still owns a 4.91 ERA due to his first start of the season but he also sports a 3.98 SIERA and has walked just 5.3% of the hitters he has faced. He'll take on an Angels team that is tied for 19th with a .319 wOBA on the season.

New York Yankees starting pitcher Nestor Cortes picked up the loss on Thursday versus the Oakland Athletics. The lefty tossed seven frames of three-run ball and allowed five hits with no walks and four strikeouts. The lefty earned a quality start, but didn't get much out of the Yankees offense to help him. Cortes had a rough 2023 campaign with a 4.97 ERA, but he has bounced back in 2024 thus far with a 3.50 ERA in his first six starts of the season. Cortes is worth rostering in most formats, but will face a tough Baltimore Orioles lineup in his next outing and might be best served on the bench in daily leagues for that contest.

Texas Rangers infielder Josh Smith continued his strong campaign versus the Seattle Mariners on Thursday. Smith went 2-for-4 with a double and a home run in the loss to the Mariners. He has seemingly come out of nowhere and been a reliable option for this offense. He's slashing 292/.393/.417 over 72 at-bats, but he's more of a bench option which limits his fantasy value.

Minnesota Twins relief pitcher Griffin Jax shut the door on the Chicago White Sox on Thursday, helping secure a 6-3 victory. Jax came in with the bases loaded and one out with a four-run lead and managed to escape with only one runner crossing home (on an error), picking up his fourth save in the process. Jax has filled in admirably as the impromptu closer after Jhoan Duran went down before the season started, posting a 2.53 ERA and 0.94 WHIP while striking out 15 batters in 10 IP. He is also 4-for-5 in save chances. Unfortunately for Jax and his fantasy managers, Duran could be back at any point as he is currently on a rehab assignment. Once he is back, Jax will likely shift back to a set-up role.

Seattle Mariners relief pitcher Andres Munoz picked up his third save of the season on Thursday, locking down the Texas Rangers in a 4-3 win. Munoz tossed up goose eggs across the board in his inning of work as he didn't allow a baserunner and didn't strike anyone out either. It was the 25-year-old's first save since April 6, as he has been used in non-save situations and has also blown a save since then. It seems like Munoz is still Seattle's highest-leverage pitcher and should see the most save chances, but his season total might be held back by being used in the seventh or eighth innings on occasion.

Los Angeles Dodgers closer Evan Phillips locked down the Washington Nationals on Thursday, helping secure a 2-1 win. Phillips looked great in this one, striking out a pair in a perfect ninth inning. For the season, the 29-year-old has been excellent, posting a 0.84 ERA and 1.13 WHIP with 13 strikeouts in 10 IP. Phillips should continue getting the bulk of the Dodgers save chances, making him an elite closing option in fantasy.

Cleveland Guardians closer Emmanuel Clase picked up his eighth save of the year after firing a perfect ninth inning during Thursday's 6-4 win over the Boston Red Sox. Clase entered the game with the top of the Red Sox order due up, but quickly sat them down after 12 pitches. The 26-year-old is enjoying a phenomenal start to the season, as evidenced by his 0.69 ERA, 0.85 WHIP and 14/1 K/BB. Clase struggled a bit last season, but he is back to being one of the top closers in baseball. Fantasy managers can expect him to finish the year near the top of the saves leaderboard.

Chicago White Sox right-hander Mike Clevinger is starting for Triple-A Charlotte on Thursday night. This will be Clevinger's first minor-league start after previously pitching in extended spring training to try and get stretched out after re-signing with the club on a one-year deal on April 2. The 33-year-old is scheduled to throw four innings or 60 pitches on Thursday and then move to five innings or 75 pitches in his next minor-league start. If Clevinger looks good after those two outings on the farm, he could be called up to the big-league roster and start make his 2024 debut for the White Sox early in May. The former fourth-round pick by the Los Angeles Angels in 2011 went 9-9 with a 3.77 ERA and 1.23 WHIP while striking out 110 and walking 40 in 24 starts for Chicago last year. He'll be a deep-league streaming option, at best, once he returns to the majors.

The Kansas City Royals placed right-hander Alec Marsh (elbow) on the 15-day injured list on Thursday with a right-elbow contusion and recalled right-hander Will Klein from Triple-A Omaha in a corresponding move. X-rays came back negative on Marsh's elbow after he was hit by a comebacker on Wednesday and forced to leave his start early against the Toronto Blue Jays, but he's still going to have to miss at least two weeks. It's unclear who will replace the 25-year-old in Kansas City's rotation moving forward. Klein will give the Royals some more depth in the bullpen. Marsh, a former second-round pick in 2019 out of Arizona State, should return to the Royals' rotation when his 15 days are up after going 3-0 with a 2.70 ERA and 1.01 WHIP in his first five starts in 2024.

Colorado Rockies outfielder Nolan Jones (back) is still out of the starting lineup on Thursday against the visiting San Diego Padres and right-hander Randy Vasquez. Jones was lifted from Tuesday's win due to back stiffness and did not appear in Wednesday's 5-2 loss. It's been a disastrous start at the plate for the 25-year-old who is hitting just .148 with one homer, two steals, and a .469 OPS across 96 trips to the plate. Following a 20/20 season that included a .297 batting average and a hefty .931 OPS in 106 games in 2023, Jones' early-season production has been wildly frustrating for fantasy managers who utilized a high pick on the promising youngster. Jake Cave will once again take over in left field while hitting seventh on Thursday afternoon.

New York Yankees utility man Oswald Peraza (shoulder) is "deep into his throwing program" and is hitting at the team's spring complex in Tampa, FLA, according to manager Aaron Boone. However, Boone also noted that the 23-year-old remains weeks away from playing in minor-league games. Peraza bounced between the Yankees and Triple-A Scranton/Wilkes-Barre last season, scuffling to a .191 average with two homers and a .539 OPS in 52 games with the Yankees while improving to a .268 average with 14 homers, 16 steals, and an .836 OPS at the Triple-A level. With third baseman DJ LeMahieu leaving his minor-league rehab game with continued foot pain, Peraza could see reps at the hot corner upon his return depending on the severity of LeMahieu's ailment.